Background: Ethic and spirituality are the important research topics for workplaces. These phenomena are the effective principle factors for human behaviors. For this, the main purpose of this research was the study of  the relationship between spirituality with individuals’ loyalty in workplace.
Methods: Research is a correlational study and statistical population were the personnel of the administrations and organizations which related to a ministry in spring of 2000. Among them, 300 personnel were selected with the use of simple random sampling. Research instruments were: the spirituality questionnaire with 58 items and eleven subscales and loyalty with 7 items. Data were analyzed using Pearson’s correlation coefficient and stepwise regression analysis.
Results: Results reveals that, eleven subscales of spirituality have significant relations with loyalty. But there are negative significant relations between neglection from development and elevation and blocks of spirituality with loyalty. The results of stepwise regression showed that there are significant relations between loyalty with religious and spiritual values with 29 percent variance explained of loyalty in first step, religious and spiritual values along with responsibility for personal development with 36.2 percent variance explained of loyalty in second step, religious and spiritual values, responsibility in personal development and positive work unit values with 40.6 percent variance explained of loyalty in third step respectively.
Conclusion: The evidences of this research showed that, the most effective and important dimensions of spirituality for loyalty are the religious and spiritual values, responsibility in personal development and positive work unit values respectively. Therefore the above dimensions should be reinforced for increasing loyalty.